The Universe of Evil is an alternate universe in which the SuperFriends are actually evil. Here, they are referred to as the Super Enemies. What passes for law enforcement in this universe is aware of the Super Enemies, and has developed ways to combat them (for instance, police helicopters are equipped with Kryptonite lasers).
Superman once accidentally traded universes with this Earth's Superman.
This reality can be considered a close parallel to Earth-148 with an early Earth-Three bent i.e. no superheroes.
Season 4 (1979): Universe of Evil